Tethered Genes Get Checked during Replication

Tethered Genes Get Checked during Replication

Although events associated with replication stress have long formed the cornerstone of checkpoint activation, questions remain about how cells maintain the integrity of replicating genomes. Now, Bermejo et al. (2011) identify a mechanism directly linking checkpoint function to the relief of topological tension at nuclear pore tethered genes.

“More time, better quality”: Nurses perceptions of the Diabetes Get Checked Programme – Summary of Results

Aim: The overall goal of this study was to determine what impact the Diabetes Get Checked (DGC) programme had on the practice of nurses, identify those factors that nurses consider contributed to the success or failure of the programme in their work setting, and identify nurses’ suggestions for improved management and outcomes for people with diabetes in the future. Background: Recent research ...

Composing Type-checked Programs

Discrete-Time Rewards Model-Checked

This paper presents a model-checking approach for analyzing discrete-time Markov reward models. For this purpose, the temporal logic probabilistic CTL is extended with reward constraints. This allows to formulate complex measures – involving expected as well as accumulated rewards – in a precise and succinct way. Algorithms to efficiently analyze such formulae are introduced. The approach is il...

Intraoperative neurophysiological monitoring during surgery for tethered cord syndrome.

AIM The tethered cord syndrome refers to a variety of lesions that can cause the conus medullaris to be low-lying or incapable of movement within the spinal canal. Permanent or temporary neurological complications were reported following surgical release. In this report, peri- and postoperative results in cases with tethered cord syndrome that were followed by multimodal intraoperative neurophy...